# of Displayed Technologies: 2 / 2


Targeting β-catenin signaling in combination with EGFR TKI enhances progression free survival and overall survival of EGFR mutant NSCLC
TS-042666 — The discovery of a novel treatment for EGFR TKI drug resistance in NSCLC.
Non-small cell lung cancer (NSCLC), which accounts for 85% of all lung cancers, is one of the leading causes of cancer-related death. Substantial progress has been made in the management of NSCLC as several driver mutations have been identified in cell communication pathways involved in lung tumor…
  • College: College of Medicine (COM)
  • Inventors: Arasada, Rajeswara Rao; Carbone, David
  • Licensing Officer: Davis, Stewart

Immunomodulating agents engineered from Notch receptor ligands: novel immunostimulatory anticancer agents and immunosuppressants
TS-036760 — Immunomodulating agents have been engineered from Notch receptor ligand extracelluar domains. These are useful for stimulating the immune system.
Immunomodulation agents help cancer and autoimmune patients suppress or stimulate extracellular domains. This is done by the administration of modular fragments in drug suitable form, giving clinicians complementary cancer therapies and immunosuppressant options. Notch, a transmembrane receptor, r…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Carbone, David; Dikov, Mikhail; Long, Nicholas; Sullivan, Brandon; Tchekneva, Elena
  • Licensing Officer: Davis, Stewart

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