TS-046454 — Original, synthetic complexes used to detoxify hemoglobin, heme, and free iron in patients suffering from hemolysis. The use
of these complexes would allow effective treatment
of various states
of hemolysis and would mitigate the numerous side effects associated with the condition. Complexes could also be used as a drug carrier for targeting CD163+ macrophages and monocytes.
Hemolysis is a burgeoning health condition that results from various pathophysioloigical conditions. It is characterized by the rupture of red blood cells, which release toxic, cell-free hemoglobin into the bloodstream. The cell-free hemoglobin further break down into heme and apoglobin, which cau…