TS-044619 — Organophosphorus (OP) poisons including sarin, VX, and novichoks are lethal agents of chemical warfare. Their toxicity is due to their direct inhibition of acetylcholinesterase (AChE), an enzyme that is vital to the nervous system via regulation of the neurotransmitter acetylcholine (ACh). AChE in…

TS-041742 — A functional fabric mat with the capability to monitor and track anthropometric and biofeedback data accompanied by an application to integrate information and securely share with healthcare providers.

TS-041485 — Using the scaffolded DNA origami molecular self-assembly process, a manufactured DNA nanostructure can be created that circumvents MDR1/MRP-1 protein efflux pump-mediated multi-drug resistance in cancer cells to deliver clinically significant concentrations of chemotherapeutics.

TS-039269 — Synthetic natural apratoxins and non-natural apratoxin analogs with improved pharmacokinetic profiles for cancer treatments and drug development applications.

TS-038065 — OSU­-SpARKFUSE is an RNA sequencing assay that detects known and novel gene fusion mutations in multiple cancer types.

TS-037639 — A novel method to increase the effectiveness and practicality of the cancer treatment drug Flavopiridol.

TS-037584 — A device for separating macromolecules in a solution of macromolecules having different molecular sizes

TS-037353 — Expansion of human hematopoietic stem and progenitor (HSPC) cells using Epidermal Growth Factor­-Like protein 7 (EGFL7).

TS-037310 — An engineered recombinant adeno-associated virus capable of targeting fat tissue previously inaccessible to this viral vector for the purposes of genetic manipulation.

TS-037264 — Novel aza-peptide reversible protease inhibitors, which permit more drug-like and selective activity than current irreversible aza-peptide containing inhibitors.