# of Displayed Technologies: 3 / 3


A novel synthetic immunomodulator and an adjuvant for vaccines
TS-038032 — A natural plant product possessing potent immunomodulatory activity, which primes T cell immune responses, and could be used for vaccine development.
While vaccines are commonly used today for a variety of diseases and have proven efficacious for disease prevention, some vaccines do not efficiently activate an immune response. Adjuvants can be included in a given vaccine to potentiate immune activation and improve the quality of the vaccine. Th…
  • College: College of Medicine (COM)
  • Inventors: Satoskar, Abhay; Ainslie, Kristy; Bachelder, Eric; Fuchs, James; Kinghorn, Douglas; Parinandi, Narasimham
  • Licensing Officer: Davis, Stewart

Phyllanthusmin and acutissimalignan A compound derivatives for anticancer and immunostimulation
TS-037721 — A group of potential antitumor arylnapthalene lactone derivatives, which may be developed as novel anticancer and immunostimulant agents.
Natural products and semi-synthetic derivatives derived from them have been used for anticancer drugs or drug leads for many years. However, side-effects such as myelosuppression and secondary leukemia have been reported. Furthermore, these natural products can be difficult to use for targeting sp…
  • College: College of Pharmacy
  • Inventors: Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Fuchs, James; Huntsman, Andrew
  • Licensing Officer: Flammang, Ann Marie

Silvestrol as an Immune Adjuvant for Vaccines
TS-014782 — Silvestrol promotes the prevention and treatment of various cancers as an immune adjuvant.
Molecular changes due to malignant tumors and toxicity of chemotherapeutic regimen suppress the immune system of cancer patients. This immunosuppression also leaves patients vulnerable to opportunistic infections and reactivation of latent viral or mycobacterial infections. Immunostimulation, or a…
  • College: College of Medicine (COM)
  • Inventors: Baiocchi, Robert; Grever, Michael; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lucas, David; Patton, John
  • Licensing Officer: Ezzell, Janel

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