TS-038403 — A method for producing therapeutic extracellular vesicles that contain functional mRNAs, miRNAs and shRNAs, for non-endocytic deliver of DNA for applications in cancer treatment and regenerative medicine.
Numerous cell types secrete extracellular vesicles (EVs), including exosomes and microvesicles. Exosomes are nano-vesicles (40–150 nm), and contain both coding and non-coding RNAs and their fragments, DNA fragments, proteins, and other cell related biomolecules. EVs and their biomolecule con…
