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Gas Sensors for Health Monitoring and Diagnostics
TS-047136 — A range of low-cost gas sensors for non-invasive diagnostic tests and health monitoring.
Exhaled human breath is a combination of hundreds of gases including inorganic molecules such as NO, NH3 or CO, and volatile organic molecules such as acetone, ethane, and isoprene. Some of these gases are produced by the body as the result of physiological processes. Known as ‘biomarkers&rs…
  • College: College of Engineering (COE)
  • Inventors: Gouma, Pelagia-Iren
  • Licensing Officer: Gooray, Arthur "Art"
System for Immobilizing the Skull during Transcranial Focused Ultrasound Ablation
TS-043964 — A non-invasive method for immobilizing the skull of a patient undergoing surgery. The device consists of pads for contacting screws from a standard stereotactic frame and a headband that result in immobilization without damage to the skin or skull.
Both stereotactic neurosurgery and transcranial focused ultrasound surgery systems have historically required a stereotactic frame to precisely position and completely immobilize a patient's head to ensure the correct location for the operation. This frame consists of multiple pins that must b…
  • College: College of Medicine (COM)
  • Inventors: Sammartino, Francesco; Beam, Dylan; Krishna, Vibhor
  • Licensing Officer: Flammang, Ann Marie
Folding Transducer Array for Compact and Deployable Wave-Energy Guiding System
TS-043186 — A novel acoustic/ultrasonic wave-energy guiding system that utilizes structural topology to enhance directional and spectral sensitivities instead of phase delay, offering exceptional versatility and adaptable performance.
Although acoustic beamforming systems that are based on phase delays can be used to enhance directional and spectral sensitivities, each source or receiver must be individually controlled by appropriate phase delays to guide the acoustic energy radiation/reception sensitivities. This results in a …
  • College: College of Engineering (COE)
  • Inventors: Harne, Ryan
  • Licensing Officer: Norris, Francis "Frank"
High-strength and Corrosion Resistant Alloy for Patient-Specific Bioresorbable Bone Fixation Hardware
TS-042526 — Novel ternary and quaternary Mg-Zn-Ca-based alloys and a heat treatment process for producing bioresorbable bone fixation implants with improved mechanical and corrosion properties
Mg-Zn-Ca-based alloys are the most promising alloy system for bone implant applications mainly due to their superior biocompatibility. For fixation applications, the ideal is a material strong enough to hold while healing (2-4 months) yet being fully resorbed after the bones have healed (6-24 mont…
  • College: College of Medicine (COM)
  • Inventors: Dean, David; Elahinia, Mohammad; Ibrahim, Hamdy
  • Licensing Officer: Norris, Francis "Frank"
Machine-Learning Algorithm for Improved Speech Intelligibility in Noise
TS-042266 — A monaural machine-learning algorithm for classifying time-frequency units in an unknown signal, which results in marked speech-intelligibly improvements in noisy signals.
A primary complaint of hearing-impaired (HI) listeners is poor speech recognition in background noise. This issue can be quite debilitating and persists despite considerable efforts to improve hearing technology. Despite considerable effort, monaural (single-microphone) algorithms capable of incre…
  • College: College of Arts & Sciences
  • Inventors: Healy, Eric; Vasko, Jordan
  • Licensing Officer: Hong, Dongsung
Junctional Tourniquet for Groin and Axillary Regions
TS-041808 — A tourniquet with a ratcheting lock to keep pressure on wounds in the groin and axillary regions. Hemostasis can be achieved while the patient is still in the field.
Patients with blood loss in the field need to be treated immediately to prevent ongoing blood loss, shock, and death; bleeding from extremity and junctional wounds is the leading cause of potentially preventable death from penetrating injuries. Direct manual pressure is effective for the initial c…
  • College: OSU Wexner Medical Center
  • Inventors: McElroy, James; Graham, Nadi; Nocera, Tanya
  • Licensing Officer: Flammang, Ann Marie
Virtual image generation of immunohistochemical stained tissue sections using an artificial neural network
TS-039781 — Realistic immunohistochemical stained tissue section databases for training, certification, and machine standards.
Immunohistochemistry (IHC) is used to determine antigen distribution in a tissue and is widely used for diagnosis of cancers and other diseases. Diagnostic and research laboratories in the United States use locally devised IHC tissue slide preparation and scanning protocols to check scanner perfor…
  • College: College of Medicine (COM)
  • Inventors: Gurcan, Metin; Lozanski, Gerard; Senaras, Caglar
  • Licensing Officer: Norris, Francis "Frank"
Perivascular Drug Delivery Nanoplatform for Preventing Restenosis After Open Surgery
TS-039004 — Pericelle: a nanoparticle based perivascular drug delivery system to prevent stenosis and failure in vascular reconstruction surgeries
Imaging and re-intervention procedures, necessary to maintain open blood vessels following vascular reconstruction surgery, are expensive. For example, the cost of maintenance for an atriovenous (AV) fistula used in hemodialysis access has been estimated at near a staggering $15,000/year. In bypas…
  • College: College of Medicine (COM)
  • Inventors: Kent, K. Craig; Chen, Guojun; Gong, Shaoqin; Guo, Lianwang; Shi, Xudong
  • Licensing Officer: Norris, Francis "Frank"
Machine-Learning Algorithm for Improved Speech Intelligibility in Noise
TS-038074 — A monaural machine-learning algorithm for classifying time-frequency units in an unknown signal, which results in marked speech-intelligibly improvements in noisy signals.
Wireless carriers receive daily complaints about poor speech recognition in background noise during calls and are constantly looking for methods to improve especially in light of recent forays into VOIP. The ability to discriminate between speech and noise in an audio signal then is an extremely i…
  • College: College of Arts & Sciences
  • Inventors: Healy, Eric; Vasko, Jordan
  • Licensing Officer: Hong, Dongsung
Six Degrees-of-Freedom Quality Assurance Phantom for Radiation Therapy Linear Accelerators
TS-037968 — The medical physics group in the Department of Radiation Oncology has devised a 6DoF phantom that is the first of its kind to fully integrate multiple routine QA tests specifically for a six degrees-of-freedom linac table.
6DoF treatment tables allow for 2 additional degrees (pitch and roll) compared to traditional 4DoF (vertical, lateral, longitudinal, and yaw) when correcting for patient setup during image-guidance prior to treatment delivery. These tables allow for more accurate patient treatments and could poten…
  • College: OSU Wexner Medical Center
  • Inventors: Woods, Kyle; Ayan, Ahmet; Gupta, Nilendu; Woollard, Jeffrey
  • Licensing Officer: Norris, Francis "Frank"

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